Healthy Aging & Longevity
Sermorelin
A short-acting GHRH analog and the longest-established growth hormone secretagogue in clinical use.
- Physician reviewed
- 503A pharmacy compounded
- Patient-specific prescription
Formats & pricing
- 15mg vial — reconstituted injectable$240
Pricing reflects the compounded preparation and physician review. Final therapy and dosing are determined only after your intake is reviewed.
Overview
What is Sermorelin?
Sermorelin is a 29-amino-acid fragment representing the biologically active portion of growth hormone-releasing hormone. Its short half-life produces a pulse closer to natural physiology than longer-acting analogs.
Mechanism
How it works
Sermorelin stimulates pituitary GHRH receptors to release endogenous growth hormone. Because pituitary feedback remains intact, the resulting release stays within the body's own regulatory limits.
Wellness support
Potential wellness support areas
These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.
- Explored for body composition and lean mass
- Discussed for sleep quality and recovery
- Potential support for energy and vitality
- Often a starting point before longer-acting analogs
Administration
Format & dosing
Nightly subcutaneous injection before bed. Sermorelin is frequently the entry protocol for patients new to growth hormone support.
Labs & monitoring
Labs, testing & monitoring
Your physician determines the final testing requirements for Sermorelin after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.
Bloodwork status
Baseline Labs Generally Required
Commonly reviewed at baseline
- IGF-1
- Comprehensive metabolic panel (CMP)
- Fasting glucose and A1c
- Lipid panel
- Thyroid panel (TSH, free T4)
Follow-up & monitoring
IGF-1 is typically rechecked at 8 to 12 weeks with fasting glucose, and dosing is titrated from there.
Who may not be a candidate
- Pregnancy or nursing
- Active malignancy without oncology clearance
- Known hypersensitivity to the preparation
- Active pituitary disease
Medication interactions
Your physician reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.
Safety
Safety & considerations
Compounded, not FDA-approved. Not appropriate with active malignancy. Injection-site reactions are the most commonly reported effect.
Regulatory status: Compounded. Evidence level: Moderate. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed physician after review of your history.
Related therapies
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CJC-1295 / Ipamorelin
Growth hormone optimization for body composition and recovery.
Baseline Labs Generally Required
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Tesamorelin
Growth hormone-releasing peptide for visceral fat reduction.
Baseline Labs Generally Required
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Tesamorelin / Ipamorelin
Dual GH secretagogue stack for fat loss and body composition.
Baseline Labs Generally Required
Physician reviewed
Every protocol is approved by a licensed physician.
503A compounded
Prepared by licensed US compounding pharmacies.
Patient-specific Rx
Prescriptions are issued in your name only.
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