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Healthy Aging & Longevity

IGF‑LR3

A modified insulin-like growth factor analog with extended activity, reserved for closely monitored protocols.

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Format
1mg vial — injectable
Price
$200 per vial
Route
Injectable
Evidence level
Limited
Regulatory status
Educational Only
Testing
Baseline Labs Generally Required

Pricing reflects the compounded preparation and doctor review. Final therapy and dosing are determined only after your intake is reviewed.

Overview

Understanding IGF-LR3

What is IGF-LR3?

IGF-LR3 is a modified form of insulin-like growth factor 1 designed to resist binding proteins, extending its active window considerably compared with native IGF-1.

Format & administration

Prescribed as a subcutaneous injection on a doctor-defined schedule. This therapy is generally reserved for patients already established in a monitored protocol.

Testing posture

Your doctor determines the final testing requirements for IGF-LR3 after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.

How it works

How IGF-LR3 works

  1. 01IGF-1 signaling drives cellular growth and protein synthesis downstream of growth hormone.
  2. 02The LR3 modification reduces binding protein sequestration, so a greater proportion remains available at receptors.
Show illustration: IGF-LR3
IGF-LR3: proposed mechanism, physiology, and reported clinical effects. Educational illustration — not a treatment guarantee.

What has been studied

Potential applications and evidence

These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.

Explored for lean tissue and recovery
Discussed within advanced body composition protocols
Potential influence on glucose metabolism
Requires close doctor oversight

Doctor-guided

A personalized approach

Your doctor determines the final testing requirements for IGF-LR3 after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.

Bloodwork status: Baseline Labs Generally Required

Commonly reviewed at baseline

  • IGF-1
  • Comprehensive metabolic panel (CMP)
  • Fasting glucose and A1c
  • Lipid panel
  • Thyroid panel (TSH, free T4)
  • Fasting insulin

Follow-up & monitoring

IGF-1 and glycemic markers are followed closely; your doctor sets a conservative recheck interval.

Medication review

Your doctor reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.

Format & dosing

Prescribed as a subcutaneous injection on a doctor-defined schedule. This therapy is generally reserved for patients already established in a monitored protocol.

Safety

What patients should know

  • Compounded, not FDA-approved. Contraindicated with active or suspected malignancy. Hypoglycemia risk warrants careful dose review, particularly in patients using insulin or glucose-lowering agents.

Who may not be a candidate

  • Pregnancy or nursing
  • Active malignancy without oncology clearance
  • Known hypersensitivity to the preparation
  • Any history of malignancy without oncology clearance
  • Hypoglycemia or uncontrolled diabetes

Regulatory status: Educational Only. Evidence level: Limited. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed doctor after review of your history.

Common questions

Frequently asked questions

Ready when you are

Find out what your body is actually asking for.

Fill out a short intake form and our care team will build a plan grounded in your labs — not a guess from a supplement aisle.