Brain, Mood & Sleep

Pinealon / PE22-28 / Selank

A three-peptide neurological protocol combining neuroprotective, neuroplasticity, and anxiolytic research profiles.

Provider Determines TestingNasal / InjectablePreclinical evidenceCompounded
  • Physician reviewed
  • 503A pharmacy compounded
  • Patient-specific prescription

Formats & pricing

  • combination vial — reconstituted injectable$270
Start my CareSee how it works

Pricing reflects the compounded preparation and physician review. Final therapy and dosing are determined only after your intake is reviewed.

Overview

What is Pinealon / PE22-28 / Selank?

Pinealon is a short peptide studied for neuronal protection, PE22-28 for neuroplasticity signaling, and Selank for anxiolytic activity — brought together in one compounded preparation.

Mechanism

How it works

Research spans neuronal oxidative stress resistance (pinealon), TREK-1 channel modulation and synaptic plasticity (PE22-28), and GABAergic and serotonergic modulation (Selank).

Wellness support

Potential wellness support areas

These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.

  • Explored for cognitive resilience
  • Discussed for mood and stress load
  • Potential neuroprotective interest
  • Used as a defined cycle with reassessment

Administration

Format & dosing

Subcutaneous injection on a physician-defined schedule, typically as a bounded cycle rather than continuous use.

Labs & monitoring

Labs, testing & monitoring

Your physician determines the final testing requirements for Pinealon / PE22-28 / Selank after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.

Bloodwork status

Provider Determines Testing

Commonly reviewed at baseline

  • CBC
  • Comprehensive metabolic panel (CMP)
  • Thyroid panel (TSH)
  • Vitamin B12

Follow-up & monitoring

Reviewed by cognitive, mood, and sleep response between cycles; labs repeated only if clinically indicated.

Who may not be a candidate

  • Pregnancy or nursing
  • Active malignancy without oncology clearance
  • Known hypersensitivity to the preparation
  • Uncontrolled psychiatric illness without co-management

Medication interactions

Your physician reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.

Safety

Safety & considerations

Compounded, not FDA-approved. Evidence for these peptides is preliminary. Disclose all psychiatric medications during intake.

Regulatory status: Compounded. Evidence level: Preclinical. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed physician after review of your history.

Physician reviewed

Every protocol is approved by a licensed physician.

503A compounded

Prepared by licensed US compounding pharmacies.

Patient-specific Rx

Prescriptions are issued in your name only.

No membership

No concierge fee and no subscription to browse or begin.

Ready when you are

Find out what your body is actually asking for.

Fill out a short intake form and our care team will build a plan grounded in your labs — not a guess from a supplement aisle.