Healthy Aging & Longevity
MOTS-C
A mitochondrial-encoded peptide studied for its role in metabolic regulation and exercise capacity.
- Physician reviewed
- 503A pharmacy compounded
- Patient-specific prescription
Formats & pricing
- 10mg vial — reconstituted injectable$180
Pricing reflects the compounded preparation and physician review. Final therapy and dosing are determined only after your intake is reviewed.
Overview
What is MOTS-C?
MOTS-C is a short peptide encoded by mitochondrial DNA rather than the nuclear genome. It belongs to a class of mitochondrial-derived peptides that have attracted research attention in metabolic and longevity science.
Mechanism
How it works
Research has examined MOTS-C in relation to AMPK activation and cellular metabolic flexibility — the ability to shift between fuel sources — as well as its expression in response to metabolic stress such as exercise.
Wellness support
Potential wellness support areas
These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.
- Explored for endurance and exercise capacity
- Discussed within metabolic health protocols
- Potential support for cellular energy production
- Studied in the context of healthy aging
Administration
Format & dosing
Typically prescribed as a subcutaneous injection several times per week rather than daily. Your physician sets the schedule.
Labs & monitoring
Labs, testing & monitoring
Your physician determines the final testing requirements for MOTS-C after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.
Bloodwork status
Recent Labs Recommended
Commonly reviewed at baseline
- Comprehensive metabolic panel (CMP)
- Fasting glucose and A1c
- Lipid panel
- CBC
Follow-up & monitoring
Metabolic markers are commonly reviewed at 12 weeks alongside energy and body-composition changes.
Who may not be a candidate
- Pregnancy or nursing
- Active malignancy without oncology clearance
- Known hypersensitivity to the preparation
Medication interactions
Your physician reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.
Safety
Safety & considerations
Not an FDA-approved product; compounded per prescription. Review diabetes medications and metabolic conditions during intake.
Regulatory status: Compounded. Evidence level: Preclinical. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed physician after review of your history.
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Physician reviewed
Every protocol is approved by a licensed physician.
503A compounded
Prepared by licensed US compounding pharmacies.
Patient-specific Rx
Prescriptions are issued in your name only.
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