What is MOTS-C?
MOTS-C is a short peptide encoded by mitochondrial DNA rather than the nuclear genome. It belongs to a class of mitochondrial-derived peptides that have attracted research attention in metabolic and longevity science.
Healthy Aging & Longevity
MOTS‑C
A mitochondrial-encoded peptide studied for its role in metabolic regulation and exercise capacity.
- Format
- 10mg vial — 2mg/mL, 5mL injectable
- Price
- $160 per vial
- Route
- Injectable
- Evidence level
- Preclinical
- Regulatory status
- Compounded
- Testing
- Recent Labs Recommended
Pricing reflects the compounded preparation and doctor review. Final therapy and dosing are determined only after your intake is reviewed.
Overview
Understanding MOTS-C
Format & administration
Typically prescribed as a subcutaneous injection several times per week rather than daily. Your doctor sets the schedule.
Testing posture
Your doctor determines the final testing requirements for MOTS-C after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.
How it works
How MOTS-C works
- 01Research has examined MOTS-C in relation to AMPK activation and cellular metabolic flexibility — the ability to shift between fuel sources — as well as its expression in response to metabolic stress such as exercise.
Show illustration: MOTS-c
What has been studied
Potential applications and evidence
These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.
Explored for endurance and exercise capacity
Discussed within metabolic health protocols
Potential support for cellular energy production
Studied in the context of healthy aging
Doctor-guided
A personalized approach
Your doctor determines the final testing requirements for MOTS-C after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.
Bloodwork status: Recent Labs Recommended
Commonly reviewed at baseline
- Comprehensive metabolic panel (CMP)
- Fasting glucose and A1c
- Lipid panel
- CBC
Follow-up & monitoring
Metabolic markers are commonly reviewed at 12 weeks alongside energy and body-composition changes.
Medication review
Your doctor reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.
Format & dosing
Typically prescribed as a subcutaneous injection several times per week rather than daily. Your doctor sets the schedule.
Safety
What patients should know
- Not an FDA-approved product; compounded per prescription. Review diabetes medications and metabolic conditions during intake.
Who may not be a candidate
- Pregnancy or nursing
- Active malignancy without oncology clearance
- Known hypersensitivity to the preparation
Regulatory status: Compounded. Evidence level: Preclinical. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed doctor after review of your history.
Common questions
Frequently asked questions
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