Brain, Mood & Sleep
DSIP
A neuropeptide studied for its relationship with slow-wave sleep and stress response.
- Physician reviewed
- 503A pharmacy compounded
- Patient-specific prescription
Formats & pricing
- 5mg vial — reconstituted injectable$180
Pricing reflects the compounded preparation and physician review. Final therapy and dosing are determined only after your intake is reviewed.
Overview
What is DSIP?
Delta sleep-inducing peptide is a naturally occurring nonapeptide first isolated from rabbit cerebral venous blood during induced sleep. Research interest concerns sleep architecture rather than sedation.
Mechanism
How it works
DSIP has been studied in relation to delta-wave sleep activity, corticotropin regulation, and stress adaptation. It is not a sedative and does not work through the pathways used by conventional sleep medications.
Wellness support
Potential wellness support areas
These areas are commonly discussed within wellness-focused protocols. They are educational statements, not medical claims or guarantees of outcome.
- Explored for deep sleep quality
- Discussed for stress adaptation
- Potential support for sleep-wake regulation
- Used where sleep depth rather than sleep onset is the concern
Administration
Format & dosing
Subcutaneous injection in the evening before bed. Dosing is typically conservative and adjusted based on your reported sleep response.
Labs & monitoring
Labs, testing & monitoring
Your physician determines the final testing requirements for DSIP after reviewing your intake. The panels below are what is commonly reviewed for this therapy — they are educational guidance, not a fixed requirement.
Bloodwork status
Provider Determines Testing
Commonly reviewed at baseline
- Comprehensive metabolic panel (CMP)
- Thyroid panel (TSH)
- Morning cortisol
Follow-up & monitoring
Sleep quality and morning alertness guide follow-up. Additional testing is at your physician's discretion.
Who may not be a candidate
- Pregnancy or nursing
- Active malignancy without oncology clearance
- Known hypersensitivity to the preparation
- Untreated obstructive sleep apnea
Medication interactions
Your physician reviews all prescriptions, supplements, and over-the-counter medications during intake before anything is prescribed.
Safety
Safety & considerations
Compounded, not FDA-approved. Review sedatives, sleep medications, and psychiatric medications with your physician before starting.
Regulatory status: Compounded. Evidence level: Preclinical. Eligibility, dosing, laboratory requirements, and follow-up care are determined exclusively by a licensed physician after review of your history.
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Every protocol is approved by a licensed physician.
503A compounded
Prepared by licensed US compounding pharmacies.
Patient-specific Rx
Prescriptions are issued in your name only.
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